Saturday, October 24, 2026 Evidence-led medical research news
The First Cohort
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Infectious Disease

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Infectious Disease

The Ebola Vaccine We Celebrated Doesn't Touch the Strain Now Burning Through Congo

Congo's Ebola outbreak has passed 1,000 cases and is rising faster than any before it, but it is caused by Bundibugyo virus, against which the licensed Ebola vaccine and antibody drugs were never designed to work.

Infectious Disease

It Grows Like a Cancer, Not a Parasite. And It's in 37% of Seattle's Coyotes.

A European strain of Echinococcus multilocularis has been found in 37 percent of Puget Sound coyotes, the first wild-host detection on the U.S. West Coast outside Alaska.

Infectious Disease

The cheaper staph antibiotic just won the biggest trial ever run

The largest randomized trial ever run for staph bloodstream infection finds the cheap generic antibiotic cefazolin works as well as the older standard, with less kidney damage and no pharma money behind the answer.

Infectious Disease

Decades of Failed Diarrhea Vaccines Kept Hitting the Wrong Coat. A WashU Team Just Found the Scissors Underneath.

A WashU-led team identified a structurally conserved patch on three mucus-cleaving enzymes that ETEC, Shigella, and other gut pathogens all use to breach the intestinal barrier, offering a single antibody target the field has chased for decades.

Infectious Disease

American Infant Mortality Just Hit a Record Low. The International Comparison Is Half an Accounting Trick. The Mississippi Gap Is Not.

Preliminary CDC data put the 2025 U.S. infant mortality rate at 5.4 per 1,000 live births, a record low. The international comparison the headlines lean on is partly an artifact of how countries count. The domestic gap is not.

Infectious Disease

The textbook said B cells take turns. A new temporal map of a malaria infection says they don't.

A new Nature Immunology temporal map of B cell responses to malaria in mice catches class-switching, clonal expansion, and somatic hypermutation overlapping from the first week, scrambling the tidy stepwise story textbooks still teach.

Infectious Disease

The Battlefield Medicine Revolution Was Built on Fake Wounds

A British prosthetics graduate is heading to NHS ambulance crews and the British military to build realistic trauma wounds, the artisan end of the twenty-year battlefield-medicine revolution that turned hemorrhage into a survivable injury.

Infectious Disease

The AI Vaccine That 'Passed' Its First Trial Three Years Ago

Cambridge finished the Phase 1 trial in 2023. The press tour arrived in 2026. The paper, when you read it, said the immunogenicity was modest.

Infectious Disease

A 16-month-old died at an Arkansas splash pad. Its chlorinator had been broken for a month.

A new global synthesis on free-living amoebae explains why a single bad month at a public splash pad is enough to kill a child, and why the CDC's existing protocol would have caught it.

Infectious Disease

Xocova clears the FDA. What it actually prevents is the smaller story.

The FDA approved Shionogi's ensitrelvir for post-exposure COVID prevention, citing a 67% relative risk reduction. Look at what the trial actually measured and a different story comes into focus.

Infectious Disease

America's Ebola Fortress: History Has Tested This Strategy, and It Failed

Washington has built a wall around the Ebola outbreak in Central Africa. The last time America tried this, the evidence says the wall leaked, and so did the response.