Astellas presented its first real-world numbers for Veozah at ENDO 2026, framed as a win. The 656-woman observational study had no placebo arm and the company's release did not mention the FDA black-box warning for liver injury.
A 17-country study finds U.S. adults in their 50s are doing worse on memory, grip strength, loneliness, and depression than their parents were. The United States is the only country going meaningfully backward.
Scripps Research published a clever chemistry redesign that let mice's immune systems recognize an entire class of fentanyl analogues. The headlines called it an overdose blocker. The mice are doing fine. Humans are years away, and the overdose decline is already happening without it.
Brain & AgingA three-year UT Dallas study tracking nearly 4,000 adults to age 94 says brain function can climb at any age. The biology is plausible. The catch is that the people measuring the gain are the same people patenting the yardstick.
Infectious DiseaseA British prosthetics graduate is heading to NHS ambulance crews and the British military to build realistic trauma wounds, the artisan end of the twenty-year battlefield-medicine revolution that turned hemorrhage into a survivable injury.
Autoimmune & InflammationA new Nature Immunology study identifies an alveolar lung-like cell hiding inside the thymus, where it appears to teach the immune system not to attack your real lungs.
CancerA Korean state lab reports that a tool compound called UNI418 strips out the DNA-repair proteins cancer cells use to escape PARP inhibitors. The data are preclinical: cell lines and mouse xenografts. UNI418 is not yet a drug.
Autoimmune & InflammationA 28-patient feasibility trial put severe gum-disease patients on three cycles of a 750-calorie ProLon diet. Inflammation markers trended lower; clinical gum measures weren't reported. The biology question is real; the data is thin.
Drugs & FDAThe Trump administration on Thursday proposed closing the product-hopping loophole that lets drugmakers reset Medicare's negotiation clock by tweaking inactive ingredients. It is the same fix the same administration quietly tabled in October.
Brain & AgingA new Cell paper finds Alzheimer's brains are riddled with the same mutations that drive blood cancers, in the immune cells that are supposed to be protecting neurons.