base-editing
2 stories tagged "base-editing"
Investigations
The Startup Selling 'Optimized' Babies Just Paid to Gene-Edit Human Embryos
Columbia scientists rewrote cholesterol and sickle-cell genes in human embryos, reaching 100 percent in embryos edited before their first division. The funder sells parents 'optimized' babies, and a germline edit like this could be inherited by every generation that follows.
InvestigationsA Gene-Editing Trial Killed a 6-Year-Old. Nature Published the Science and Left Her Out of the Record.
Her parents paid $860,000 to base-edit their daughter's brain. She died of an immune reaction within a week, the trial's fatal outcome was never disclosed, and the Nature paper built on the same work never names her.