fibroblasts
2 stories tagged "fibroblasts"
Autoimmune & Inflammation
Oxford Found the Cells That May Mark Which Joints Rheumatoid Arthritis Attacks. They Were There Before You Were Born.
The joints rheumatoid arthritis attacks and the ones it spares are built differently in the womb, seeded with different cells before a single joint ever swells.
Autoimmune & InflammationWhy Anti-TNF Keeps Failing So Many Crohn's Patients: The Drug Never Reached the Cell Holding the Disease Open
Anti-TNF biologics have muzzled the immune system for 25 years, and up to 46 percent of Crohn's patients still fail them. A single-cell atlas points at the structural cells of the gut wall, epigenetically rewired into a state the drugs were never built to reach.