il-22
2 stories tagged "il-22"
Autoimmune & Inflammation
Microfold Cells Got Filed as the Gut's Mail Slot. They Were Organizing Its Defense.
The specialized cells that hand your gut bacteria to the immune system turn out to build the niche that keeps antimicrobial defense switched on, and the same signal that makes them wires in the brake.
Autoimmune & InflammationThe Gut's Doorway Cells Have a Second Job: Landlord to Its Barrier Defenders
Microfold cells were filed away as passive antigen samplers. In mice, they turn out to build and staff the niche that keeps the gut's IL-22 defenders alive, the cytokine that fortifies the intestinal barrier and keeps sampled bacteria contained inside its immune outposts.