orforglipron
2 stories tagged "orforglipron"
Metabolic & Weight
Orforglipron Reaches Deep Into the Brain's Reward Circuit and Turns the Dopamine Down
In mice engineered with human GLP-1 receptors, the new oral pills reached the central amygdala, a deep reward hub, and thinned the dopamine payoff of eating for pleasure. The government's addiction institute is already watching.
Metabolic & WeightThe Obesity 'Revolution' Everyone's Promising Comes From People Who'd Cash In On It
A new commentary says the GLP-1 era is just the prelude to a bigger obesity "revolution." The authors have direct financial stakes in what comes next, and the celebrated new pill loses less weight than the shot.