setmelanotide
2 stories tagged "setmelanotide"
Metabolic & Weight
A Brain Protein Made Female Mice Overeat Fat, and the $441,000 Obesity Drug Worked Weakest on Them
Dietary fat switches on an appetite-protecting brain protein in male mice but not females. Delete it and the females overeat fat, gain more weight, and setmelanotide, the $441,000-a-year MC4R obesity drug, loses much of its appetite-suppressing punch on them.
Drugs & FDAA $440,000 Drug Proved This Obesity Was Never About Willpower
Brain-tumor surgery can wreck the hypothalamus and leave hunger permanently switched on. Setmelanotide restored the missing signal in a real placebo-controlled trial, then arrived priced near half a million dollars a year.