Brain & Aging
107 stories · Page 5 of 5
A molecule your body already makes coaxed exhausted brain cells back to fighting Alzheimer's
Spanish and Swiss researchers report that OLE, a fatty-acid amino-acid the body already makes, coaxed sluggish microglia to surround amyloid plaques and improve memory in Alzheimer's mice.
Brain & AgingA viral diabetes-and-dementia explainer left out the trial that just killed its big drug story
A widely shared "ten ways diabetes and dementia are linked" explainer is going around this week, and it skips the Phase 3 trial that, weeks earlier, demolished its brain-protection story for semaglutide.
Brain & AgingA 272,000-Person Study Linked Higher Tyrosine to Shorter Lifespans in Men. The Supplement Aisle Sells It for Focus.
A UK Biobank analysis of 272,475 people using Mendelian randomization links higher blood tyrosine to about 0.91 fewer years of life in men, with no signal in women. The amino acid is sold widely as a focus and stress supplement. The study measured blood levels, not pills.
Brain & AgingThe Shingles Vaccine Keeps Cutting Dementia Risk. The Reason May Not Be the Shingles.
Four big studies now tie the shingles vaccine to lower dementia risk. The most useful finding is that the same effect shows up with an RSV vaccine that shares its adjuvant.
Brain & AgingMiddle-aged Americans Are Weaker, Lonelier, and Forgetting More Than Their Parents Did at the Same Age
A 17-country study finds U.S. adults in their 50s are doing worse on memory, grip strength, loneliness, and depression than their parents were. The United States is the only country going meaningfully backward.
Brain & AgingBrain Gains Into Your 90s Are Probably Real. The Index Measuring Them Has a Patent Pending.
A three-year UT Dallas study tracking nearly 4,000 adults to age 94 says brain function can climb at any age. The biology is plausible. The catch is that the people measuring the gain are the same people patenting the yardstick.
Brain & AgingThe Same Mutations That Drive Blood Cancer Keep Turning Up in Alzheimer's Brains
A new Cell paper finds Alzheimer's brains are riddled with the same mutations that drive blood cancers, in the immune cells that are supposed to be protecting neurons.
Brain & AgingNitrate from spinach behaves nothing like nitrate from tap water. A 27-year cohort says the brain can tell.
54,804 Danes followed for a quarter-century: less dementia from vegetable nitrate, more from drinking water. The risk signal shows up at roughly one-ninth of what the US EPA still permits.
Brain & AgingDisappointment, Not Reward, Is What Breaks a Habit. Half of Older Adults Are on Drugs That Blunt Acetylcholine.
An OIST team caught the mouse brain firing acetylcholine the moment an expected reward failed to land. That surge is what lets the animal switch strategy. Close to half of community-dwelling older adults are on drugs that block the same receptors.
Brain & AgingThe Alzheimer's Drug That Bets the Plaques Are a Symptom
An ETH Zurich team spent nearly twenty years tracing why Alzheimer's nerve cells run out of energy, and the answer points to a protein the amyloid-clearing drugs never touched.
Brain & AgingHarvard Just Mapped How a Mouse Smells, and It Quietly Rewrites What Smell Loss Means
Harvard used MERFISH to image roughly 1,100 odorant receptors across the mouse nose at once and found tidy stripes, not chaos. The clinical stakes for smell loss just got harder to wave off.