drug-resistance
3 stories tagged "drug-resistance"
Cancer
The Compound That Outsmarts Cancer's Defenses: Eight Cell Lines, a Few Mice, and a Startup
Baylor researchers say CS18 dismantles the survival switch tumors use to resist treatment. It works in eight cell lines and a handful of mice, and its inventors just incorporated a company around it.
CancerThe Evolutionary Fix for Drug Resistance Works Best on a Tumor Too Small to Find
City St George's mathematicians say hitting a tumor at its weakest moment can drive it extinct. Their own model clears 95 percent only below 7 million cells, far smaller than any tumor a scan can find.
CancerA Korean lab found cancer's DNA-repair off-switch. In a mouse.
A Korean state lab reports that a tool compound called UNI418 strips out the DNA-repair proteins cancer cells use to escape PARP inhibitors. The data are preclinical: cell lines and mouse xenografts. UNI418 is not yet a drug.