mash
3 stories tagged "mash"
Metabolic & Weight
A Cleanup Enzyme Fades as Fatty Liver Turns Dangerous, and Restoring It Cut the Damage in Mice
Cedars-Sinai researchers found liver cells lose an enzyme called UBE2N as fatty liver slides toward scarring, and restoring it reduced fat, inflammation and scarring in mice. It lands just as MASH has become a drug market.
Metabolic & WeightThis Weight-Loss Hormone Protected Mouse Livers Without a Pound Lost. Novo Nordisk Supplied It and Put Two Scientists on the Study.
The hormone works through the same brainstem switch that makes weight-loss drugs nauseating, and the company developing it supplied the compound, funded the mouse study, and put two of its scientists on the author list.
Metabolic & WeightA Gut Microbe Was Feeding Ammonia to Sick Livers. A Michigan Peptide Cut Off the Supply in Monkeys.
The compound reversed severe fatty liver in monkeys by starving one ammonia-making gut bacterium. It also comes from a company its lead inventor founded, and no human has taken it for this.