Sunday, October 18, 2026 Evidence-led medical research news
The First Cohort
Medical research, with the receipts

muscle

6 stories tagged "muscle"

Metabolic & Weight

Hard Intervals Held the Lean Mass That Gentle Cardio Lost. The Researchers Say Don't Oversell It.

Treadmill intervals held onto lean mass in healthy older adults while steady moderate cardio chipped away at it. The researchers' own verdict on the difference: small, and not clinically meaningful once you account for the wobble in a body scan.

Nutrition & Food

MRI Found Fat Marbled Inside the Thigh Muscles of Heavy Ultra-Processed Eaters, and Calories Didn't Explain It

MRI scans of 615 adults found more fat marbled inside the thigh muscle the more ultra-processed food people ate, and the link held after adjustment for calorie intake, exercise, and fat intake.

Metabolic & Weight

Berkeley Dusted Off a Shelved 1970s Fat Compound That Burns Energy Instead of Appetite, and in Mice It Spared the Muscle

GLP-1 drugs quiet your appetite, and along with the fat they can pull out a real chunk of muscle. A shelved acetyl-CoA carboxylase inhibitor from the 1970s went after the other lever, energy burned, and in obese mice it left the lean mass alone.

Metabolic & Weight

Switch Off One Protein Called Mitch, and Cells Start Eating Their Own Fat

Women with obesity carry more of it. Disable it in mice and they turn lean and muscular at once, the opposite of what the injectable weight-loss drugs do to your body.

Nutrition & Food

They Call It Aging. Sometimes It's a Vitamin Your Doctor Forgot to Check.

New Cornell research explains how B12 deficiency starves muscle of energy, and why the standard test your doctor orders can call the problem aging.

Nutrition & Food

The Protein Numbers on the Government Charts Were Never Meant to Help You Thrive

A new Frontiers in Nutrition perspective argues official protein and exercise guidelines were built to prevent deficiency, not to maximize healthspan, and that older adults in particular need far more.