neurodegeneration
7 stories tagged "neurodegeneration"
Psilocybin Trial's Banked Blood Shows Parkinson's Inflammation Markers Still Lower a Month Later
Five inflammatory signals were still below baseline a month after the second psilocybin session, in blood banked from nine Parkinson's patients in an uncontrolled UCSF pilot whose investigators carry psychedelic-industry ties.
Brain & AgingIn Lab Tests, the Alzheimer's Fragment Labeled 'Non-Amyloidogenic' Builds Amyloid Faster Than Amyloid Beta
For decades the alpha pathway was billed as the safe way to cut the Alzheimer's precursor protein. Its leftover fragment, p3, builds fibrils in less than half the time amyloid beta needs in lab tests, forms ring-shaped pores, and turns up in plaques where a common antibody stain can't tell the two a
Brain & AgingI Track My REM Sleep Every Night. This Study Made Me Stop Trusting the Number.
The viral headline says more REM sleep guards you against 83 diseases. But a brain sliding toward Parkinson's shreds REM years before diagnosis, and the study's own two-year exclusion test quietly agrees.
Brain & AgingDirty Air Is Linked to 16 Percent More Inflammation in Your Blood. Does That Damage Reach Your Brain?
Each step up in long-term fine-particle exposure is tied to nearly 16 percent higher inflammation in older adults' blood, and a CHARLS analysis asks whether that same signal is what wears down the aging brain.
Brain & AgingThe Alzheimer's Field Spent Decades Trying to Destroy These Droplets. A Baylor Lab Says the Droplets Were Never the Problem.
A Baylor lab reports that tubulin redirects Tau and alpha-synuclein away from toxic clumping in the test tube. It is elegant mechanism work, and not yet a drug, an animal, or a person.
Brain & AgingThe amyloid-versus-tau war in Alzheimer's might be the wrong fight
A four-person UC Riverside chemistry group argues amyloid beta and tau compete for the same microtubule binding sites, a unifying mechanism that cuts under Alzheimer's research's three-decade amyloid-versus-tau fight.
Brain & AgingThe Same Mutations That Drive Blood Cancer Keep Turning Up in Alzheimer's Brains
A new Cell paper finds Alzheimer's brains are riddled with the same mutations that drive blood cancers, in the immune cells that are supposed to be protecting neurons.