preclinical
28 stories · Page 2 of 2
A heart-attack drug just regrew kidney tissue in mice, and the receipts have no pharma on them
A UCLA monoclonal antibody designed to help hearts heal after a heart attack also repaired injured kidneys in mice, and it was developed without a dollar of pharma money.
CancerA Korean lab found cancer's DNA-repair off-switch. In a mouse.
A Korean state lab reports that a tool compound called UNI418 strips out the DNA-repair proteins cancer cells use to escape PARP inhibitors. The data are preclinical: cell lines and mouse xenografts. UNI418 is not yet a drug.
Autoimmune & InflammationFish oil rewired the T-cells in non-obese diabetic rats, and the glucose moved with them
A Brazilian team gave EPA-heavy fish oil to a non-obese diabetic rat strain for eight weeks. Glucose, insulin sensitivity, and lipids all moved in the friendlier direction. The T-cell balance shifted alongside them, and that is the part of the paper worth chewing on.
Nutrition & FoodYale's Olive Oil Cancer Story Did Not Actually Test Olive Oil
A Yale mouse study reported in Cancer Discovery is being sold as proof that olive oil fuels pancreatic cancer. The lab fed the mice purified oleic acid, the effect only showed up in males, and no one has tested it in a person.