mitochondria
6 stories tagged "mitochondria"
The Leucine Trick That Boosts Your Mitochondria Also Shielded Lung Tumor Cells in the Lab
Leucine keeps cells from shredding the import docks on their mitochondria. In lab lung tumor lines rich in leucine's chemical family, the same biology came with resistance to a drug built to starve them.
Nutrition & FoodTwo Labs on Two Continents Watched a Pomegranate Compound Relax Stiff Mouse Hearts
Heart failure with preserved ejection fraction has few disease-modifying options. A gut metabolite from pomegranates and walnuts, already sold as a supplement, improved measures of heart function up to 80 percent in mice.
Brain & AgingScientists Quieted Aging Inflammation in Mice by Starving Zombie Cells, Not Killing Them
For years the anti-aging plan was to hunt down and kill the senescent cells driving inflammation. A Mayo and Sanford Burnham team quieted that inflammation in mice instead, by blocking the carrier that feeds their mitochondria the acetyl-CoA used to pry open inflammatory genes.
Metabolic & WeightSwitch Off One Protein Called Mitch, and Cells Start Eating Their Own Fat
Women with obesity carry more of it. Disable it in mice and they turn lean and muscular at once, the opposite of what the injectable weight-loss drugs do to your body.
Nutrition & FoodThey Call It Aging. Sometimes It's a Vitamin Your Doctor Forgot to Check.
New Cornell research explains how B12 deficiency starves muscle of energy, and why the standard test your doctor orders can call the problem aging.
Brain & AgingThe Alzheimer's Drug That Bets the Plaques Are a Symptom
An ETH Zurich team spent nearly twenty years tracing why Alzheimer's nerve cells run out of energy, and the answer points to a protein the amyloid-clearing drugs never touched.