neuroinflammation
6 stories tagged "neuroinflammation"
The Amino Acid That Sharpened Old Mice's Memory Made Neuron Loss Worse in Alzheimer's Mice
D-serine improved memory in old mice in a 2023 study now recirculating as news. Given to Alzheimer's model mice, the same amino acid made neuron loss worse, and the human trial behind the hype was a single dose.
Brain & AgingDrugs Aimed at This Week's Brain-Inflammation Target Have Already Failed in Patients
AstraZeneca and Pfizer each took a P2X7 blocker into rheumatoid arthritis trials, and neither beat placebo. A Birmingham lab now says the same receptor could tame inflammation in Alzheimer's and Parkinson's.
Autoimmune & InflammationThe Cell Long Dismissed as Brain 'Glue' Is Presenting Your Nerves to the Immune System
For a century, astrocytes were dismissed as the brain's passive scaffolding. Now researchers have caught them inside multiple sclerosis lesions dressed as immune cells, arming the very T cells that attack the brain.
InvestigationsBrain on Fire: Ottawa's Vaccine-Injury Program Spent More on Its Contractor Than on the Injured
Fifty injured Canadians testified in Ottawa over four days, and Health Canada did not show. The compensation program has spent more on its contractor's overhead than on the people it was built to pay.
Brain & AgingThe Fat Molecule That Rides From Your Waistline to Your Brain, and Feeds Alzheimer's Once It Gets There
In obese mice, a membrane fat called phosphatidylethanolamine packed into tiny vesicles, rode to the brain, and sabotaged the immune cells that clear amyloid. An investigational drug reversed it, in mice.
Brain & AgingA molecule your body already makes coaxed exhausted brain cells back to fighting Alzheimer's
Spanish and Swiss researchers report that OLE, a fatty-acid amino-acid the body already makes, coaxed sluggish microglia to surround amyloid plaques and improve memory in Alzheimer's mice.