drug-development
5 stories tagged "drug-development"
The 'Bone-Building Switch' Is Back in the Headlines. It Was Tested in Mice, and Only Mice
A publicly funded Leipzig compound rebuilt bone in ovariectomized mice, 8 per treated group. More than a year later the same experiment is still being sold to readers as a way to keep their bones strong for life.
Brain & AgingThis Week's Autism 'Breakthrough': A Rare Mutation, an Injection Into Mice, and Not One Human Patient
An injection that silences one gene rescued social behavior in mutant mice and a dish of human cells. The headlines called it an autism therapy. No autistic person has received it, and the gene it targets is mutated in a small fraction of cases.
Infectious DiseaseDavid Ho's Lab Built an Antibody to Neutralize Nearly Every Strain of HIV. Its First Test in People With the Virus Held for Two Weeks.
Fifty-four volunteers, nine with HIV, and just three with virus still in their blood. The engineered antibody drove their viral load down as much as ninetyfold, then lost the ground within a week as it drained away.
Brain & AgingThe amyloid-versus-tau war in Alzheimer's might be the wrong fight
A four-person UC Riverside chemistry group argues amyloid beta and tau compete for the same microtubule binding sites, a unifying mechanism that cuts under Alzheimer's research's three-decade amyloid-versus-tau fight.
Brain & AgingThe Alzheimer's Drug That Bets the Plaques Are a Symptom
An ETH Zurich team spent nearly twenty years tracing why Alzheimer's nerve cells run out of energy, and the answer points to a protein the amyloid-clearing drugs never touched.