longevity
16 stories tagged "longevity"
Same Diet, Same 15 Pounds: Only the Women Who Ate in an 8-Hour Window Got Sharper
Two groups of older women cut the same calories and lost the same 15 pounds over six months. The ones who packed eating into an 8-hour window still scored better on problem-solving, from a 47-person pilot that hasn't been peer-reviewed.
Metabolic & WeightThe Mice Ate More and Got Leaner. The Switch Was One Amino Acid, Turned Down.
USC mice on a low-protein, methionine-tuned diet ate as many calories as the junk-food group and still lost fat, while their own bodies pumped out more GLP-1. The scientist behind it also owns the company selling longevity diets.
InvestigationsA Pharma-Funded Nonprofit Is Lobbying the FDA to Kill Seven Peptides It Can't Sell You
The Partnership for Safe Medicines has deep ties to the drug lobby. Now it's urging the FDA to permanently block BPC-157, MOTS-c and five other off-patent peptides that compounding pharmacies sell cheap.
Metabolic & WeightOld Muscle Forgets How to Clean Itself. A Gene Called DEAF1 Is Why, and Exercise Silences It.
In aging muscle one gene keeps the growth pathway jammed on and the cleanup crew locked out. Exercise suppresses it in flies and mice, no pill required.
Brain & AgingLongevity Clinics Sell Growth Hormone by the Vial. In Deep Sleep, Your Brain Makes It Free.
The muscle-building, fat-burning hormone that anti-aging clinics inject at a premium is the same one your hypothalamus releases every night you reach deep sleep. Berkeley mapped how, in mice, and the headline is already running ahead of the biology.
Brain & AgingSenescence Built Your Hands Before It Ever Aged Your Skin
Cellular senescence, the process blamed for aging and disease, is also how an embryo sculpts fingers and clears its own tissue. That double life scrambles the anti-aging industry's tidy 'kill the zombie cells' pitch.
Metabolic & WeightThe Belly Fat You Gain After 40 Comes From a Cell That Barely Existed in Your Twenties
Transplant old fat stem cells into a young mouse and they keep churning out fat; young ones in an old mouse stay quiet. In mice, the fat-making program travels with the cell, not the body around it.
Brain & AgingThey Told Older Adults the Pill Was Fake. Their Memory Got Better Anyway.
A 90-person Italian trial gave older adults inert pills and told one group flat-out they were fake. That group improved as much as the deceived one. Here is what that does and doesn't prove.
Nutrition & FoodA Cheap Amino Acid Pulled Mice Back From a Cytokine Storm. The Twist Is Which Organ Did the Saving.
A Salk Institute mouse study found that dietary methionine cut deaths from severe inflammation by boosting the kidneys' ability to flush pro-inflammatory cytokines into urine, without blunting the immune response to infection.
Brain & AgingThe Brain Was Starving Before the Plaques Showed Up: Alzheimer's Metabolic Reframe Has a Case, Not a Trial
A rising camp says failing mitochondria, not amyloid plaques, may drive Alzheimer's first. The biology is compelling and the amyloid monoculture earned its reckoning, but the metabolic side has its own retractions and not one human trial showing it works.
Nutrition & FoodBrewed tea has the longevity receipts. The supplement aisle has a liver problem.
A 2025 review finds 1.5 to 2 cups of brewed tea daily correlate with about 10% lower all-cause and 14% lower cardiovascular mortality. The EGCG-extract supplements built on the same chemistry have been linked to over 100 liver-injury cases, while bubble tea can match a Coke for sugar.
Brain & AgingThe Supervised Prehab Worked. The Home Version Hospitals Want to Sell You Did Not.
Two randomized trials in older surgical patients, one positive and one null, draw the same line under what "prehabilitation" actually requires, and why the version a hospital can hand you on paper did nothing.
Brain & AgingA 272,000-Person Study Linked Higher Tyrosine to Shorter Lifespans in Men. The Supplement Aisle Sells It for Focus.
A UK Biobank analysis of 272,475 people using Mendelian randomization links higher blood tyrosine to about 0.91 fewer years of life in men, with no signal in women. The amino acid is sold widely as a focus and stress supplement. The study measured blood levels, not pills.
Brain & AgingMiddle-aged Americans Are Weaker, Lonelier, and Forgetting More Than Their Parents Did at the Same Age
A 17-country study finds U.S. adults in their 50s are doing worse on memory, grip strength, loneliness, and depression than their parents were. The United States is the only country going meaningfully backward.
Brain & AgingBrain Gains Into Your 90s Are Probably Real. The Index Measuring Them Has a Patent Pending.
A three-year UT Dallas study tracking nearly 4,000 adults to age 94 says brain function can climb at any age. The biology is plausible. The catch is that the people measuring the gain are the same people patenting the yardstick.
Autoimmune & InflammationThe Herbal Steroid That Hits Pharma's Holy-Grail Kidney Target
A Shanghai lab reports a steroid from a Yunnan mountain plant, already sold over the counter to bodybuilders, suppresses the same kidney-fibrosis pathway Big Pharma keeps circling and never quite closes on.