lupus
3 stories tagged "lupus"
Autoimmune & Inflammation
Lupus Hits Nine Women for Every Man, and the Reason May Be Hiding in DNA Both Sexes Share
Scientists sequenced more than 1.25 million immune cells and found over 1,000 genetic switches set differently in men and women, with the female side tuned for stronger inflammation. It may help explain why lupus hits nine women for every man.
Autoimmune & InflammationA Lung Atlas Found 1,000 Autoimmune-Risk Genes That Blood Studies Missed
For two decades, geneticists mapped thousands of autoimmune-risk variants that sat silent in blood cells. A 1.1-million-cell lung atlas shows the effects switch on only in immune cells lodged in tissue.
Autoimmune & InflammationA Map of 1.1 Million Lung Immune Cells Finds the Genetic Risk for Autoimmune Disease in Tissue, Not Blood
Researchers at La Jolla mapped genetic activity in 1.1 million lung immune cells and found about 1,000 genes whose activity is tuned by disease-risk variants only inside tissue, plus 1,700 that read differently in women than in men.