cancer
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The Reason Immunotherapy Bounces Off Prostate Cancer: Tumors Chew Off a Genetic Tail to Blind the Immune System
Prostate tumors overproduce a protein that destroys the immune system's docking targets. A CRISPR tool that blocks the trick made checkpoint drugs work again, so far only in mice.
CancerThe Genes Driving Cancer's Growth Are the Same Ones It Keeps Breaking
The same super-enhancers that make a tumor grow keep snapping its DNA, and the botched repairs are where the next mutations come from. The finding is real, careful, and already a year old.
CancerIn 2021, Creatine Spread Cancer in Mice. This Week, a UCLA Lab Said It Fights It.
A UCLA study found creatine energized cancer-fighting immune cells in mice and lab dishes. It was never tested in a patient, and a separate line of research says the same supplement feeds metastasis.
InvestigationsThe Phone-Radiation Study Everyone Called a Debunking Was Too Small to Find the Tumor
Japan and Korea spent two years 'validating' the NIH finding that cell-phone radiation gave rats heart tumors. They used one dose, one sex, and too few animals to detect it. Korea's rats grew the tumor anyway.
CancerA Week Instead of a Month: The Faster Prostate Radiation Was Only "As Safe" on the Coarser Ruler
PACE-C put five-fraction radiation against the four-week course in 1,208 men. On the old grading scale they matched. On the finer one the short course logged 17 percent bowel toxicity against 10 percent, and the trial still can't say whether the shorter beam controls cancer as well.
CancerThe Same Cancer Mutation, Opposite Effects: What 581 Mouse Tumors Say About Who Gets Sick
Cambridge and Yale gave four strains of mice one identical dose of a carcinogen. The tumors converged on the same pathway but took four different genetic routes to get there, and today's screening ignores the reason.
InvestigationsBPA Sits in 90% of Us. The Cancer Studies Sample It With a Method That Was Never Going to Find Anything.
Bisphenol A shows up in more than nine of ten Americans, yet California's reviewers just called the cancer evidence 'inadequate,' because the studies measure a chemical the body clears in hours from a single urine sample.
CancerThe Evolutionary Fix for Drug Resistance Works Best on a Tumor Too Small to Find
City St George's mathematicians say hitting a tumor at its weakest moment can drive it extinct. Their own model clears 95 percent only below 7 million cells, far smaller than any tumor a scan can find.
CancerPregnancy Stations Killer T Cells in the Milk Ducts, and a Decade Later They Haven't Left
Melbourne researchers found that pregnancy stations killer T cells in the milk ducts, where they persist for at least a decade and track with better breast cancer outcomes. Now the race is on to summon them with a hormone shot instead of a pregnancy.
CancerWhether a T Cell Keeps Killing Cancer or Quits Is Written in How Its Genome Folds
Exhausted CD8 T cells are why checkpoint drugs and CAR-T so often stall. New maps of the 3D genome show their fate is set by how the DNA is physically folded, and by CTCF, the protein that does the folding.
CancerOne Protein Keeps Your T Cells in the Fight. The Same Protein Feeds Autoimmune Disease.
In mice, deleting the LEF1 gene collapsed the reserve T cells that sustain the fight against chronic infection and cancer. The same deletion protected against autoimmune diabetes.
CancerA Cancer Algorithm Found Answers in 71 Children. The 'Quantum' Label Is the Least Interesting Thing About It.
A University of Utah team used the linear algebra of quantum mechanics to pull two survival predictors from just 71 neuroblastoma patients. The science is real. The word doing the marketing is not.
InvestigationsA Top Cancer Scientist, a Deleted Study, and the Question Washington Won't Fund
A June 2026 Senate subcommittee hearing centered on a Brown University cancer researcher's review of 333 post-vaccination cancer case reports, and on the retractions, censorship, and cyberattack that met it.
CancerA Repair Gene Turns Saboteur, and a $4 Billion Drug Class Sees an Opening
A Penn State lab found that too much of the DNA repair gene EXO1 makes ordinary tumors behave like BRCA-mutant ones in a dish, and respond to the same drugs. The science is clean. The market context is not.
CancerThe "Secret Reason" Cancer Drugs Stop Working Was Published in February
A Montreal team's antibody against the SLAMF6 brake on T cells made the rounds this week as a fresh discovery. The paper went up in February, the work is in mice, and the antibody has not been given to a person.
CancerIvermectin and Cancer: The Review the Horse-Paste Crowd Wasn't Supposed to Get
A 2025 systematic review finds coherent anticancer biology in ivermectin across ten tumor types. The human evidence to match it does not exist. The question of why is what the punchline was designed to bury.
CancerA Korean lab found cancer's DNA-repair off-switch. In a mouse.
A Korean state lab reports that a tool compound called UNI418 strips out the DNA-repair proteins cancer cells use to escape PARP inhibitors. The data are preclinical: cell lines and mouse xenografts. UNI418 is not yet a drug.
Drugs & FDAThe Macaques Get a Reprieve. Pharma Gets a Faster Pipeline.
The FDA's new draft guidance lets oncology developers cut animal studies for certain biologics and conjugated products. The replacement laboratory methods are still being validated.
CancerSix melanoma patients, six weeks, one common variable: the question oncology is choosing not to study
An oncologist's bedside pattern, a Senate hearing, and a mechanism paper sitting in a mainstream oncology journal: the case that repeated mRNA boosters may be lifting the brakes off cancers oncologists thought they had quiet is no longer fringe enough to wave away.
CancerALTAIR Missed Its Primary Endpoint. The Press Tour Found Something Else.
A phase 3 trial testing chemotherapy in ctDNA-positive colorectal cancer patients missed its primary endpoint at p=0.107, and a post-hoc reanalysis is doing the public-facing work.
InvestigationsA Senate Subcommittee Just Put the COVID Shot Cancer Question on the Record
A Senate Homeland Security subcommittee took testimony on whether mRNA COVID shots can plausibly cause cancer, and on the parallel campaign to keep that question out of the journals. Dr. John Campbell walked his audience through it.
CancerPancreatic cancer's undruggable wall just cracked. The follow-up is 8.5 months and the money was already placed.
Revolution Medicines' daraxonrasib nearly doubled median overall survival versus chemotherapy in previously treated metastatic pancreatic cancer at ASCO 2026, with 8.5 months of follow-up and a two-billion-dollar Royalty Pharma deal already riding on what comes next.
InvestigationsA Senate hearing finally put the cancer question on the record. The journal notice had been up for months.
Sen. Ron Johnson's June 3 subcommittee hearing on plausible mechanisms linking mRNA injections to cancer, the South Korean cohort behind it, and the editorial notice Springer had posted on the paper months earlier.