immunology
6 stories tagged "immunology"
In Tuberculosis, the Cell We Called 'Neutral' Is the One Torching the Lung
In the people whose latent TB roared into active disease, the airways filled with neutrophils, half of them flipping on an interferon alarm, while their T cells were pushed to exhaustion and death.
Autoimmune & InflammationThe Allergy Cell Everyone Wanted Dead Turns Out to Run Your Gut Lining and Your Metabolism
Eosinophils were the villain of asthma and allergy, the cell whole-body drugs are built to erase. A decade of tissue biology says they also seal your gut, feed your antibodies, and tune your fat, and the trials never measured any of it.
CancerPregnancy Stations Killer T Cells in the Milk Ducts, and a Decade Later They Haven't Left
Melbourne researchers found that pregnancy stations killer T cells in the milk ducts, where they persist for at least a decade and track with better breast cancer outcomes. Now the race is on to summon them with a hormone shot instead of a pregnancy.
Infectious DiseaseMost People's Bodies Quietly Beat TB. The Ones Who Lose Are Drowning Their Own T Cells.
A new single-cell study of the airways of TB-exposed people finds that progression to disease tracks with a neutrophil flood that smothers protective T cells, with type I interferon as the switch.
Infectious DiseaseThe textbook said B cells take turns. A new temporal map of a malaria infection says they don't.
A new Nature Immunology temporal map of B cell responses to malaria in mice catches class-switching, clonal expansion, and somatic hypermutation overlapping from the first week, scrambling the tidy stepwise story textbooks still teach.
Autoimmune & InflammationYour Thymus Quietly Stages a Lung. Researchers Just Named the Cell Playing the Part.
A new Nature Immunology study identifies an alveolar lung-like cell hiding inside the thymus, where it appears to teach the immune system not to attack your real lungs.