Sunday, June 14, 2026 Evidence-led medical research news
The First Cohort
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neuroscience

4 stories tagged "neuroscience"

Brain & Aging

Disappointment, Not Reward, Is What Breaks a Habit. Half of Older Adults Are on Drugs That Blunt Acetylcholine.

An OIST team caught the mouse brain firing acetylcholine the moment an expected reward failed to land. That surge is what lets the animal switch strategy. Close to half of community-dwelling older adults are on drugs that block the same receptors.

Brain & Aging

The Alzheimer's Drug That Bets the Plaques Are a Symptom

An ETH Zurich team spent nearly twenty years tracing why Alzheimer's nerve cells run out of energy, and the answer points to a protein the amyloid-clearing drugs never touched.

Metabolic & Weight

A gut hormone keeps showing up in the brain's reward circuit, and 600,000 veterans just gave us the biggest hint yet that it matters

A VA cohort of 606,000 diabetic veterans on GLP-1 drugs showed lower risks of new substance use disorders and large drops in overdose and drug-related death versus a peer diabetes drug. The mechanism story is where it gets interesting.

Brain & Aging

Harvard Just Mapped How a Mouse Smells, and It Quietly Rewrites What Smell Loss Means

Harvard used MERFISH to image roughly 1,100 odorant receptors across the mouse nose at once and found tidy stripes, not chaos. The clinical stakes for smell loss just got harder to wave off.