metabolism
12 stories tagged "metabolism"
Eating After Dinner Tracked With More Fatty Liver and Cirrhosis in Nearly 200,000 Americans
Across nearly 200,000 nurses and health professionals, eating after dinner or bedtime tracked with 20 to 30 percent more fatty liver disease and cirrhosis. Nobody can patent a closed kitchen.
Nutrition & FoodSame Calories on Paper, 116 Fewer Absorbed: What Your Gut Microbes Do With a Whole-Food Diet
On calorie-matched menus, 17 adults absorbed about 116 fewer calories a day eating whole foods than eating processed ones, with no measurable rise in hunger, and the century-old Atwater arithmetic undercounted the processed plate.
Nutrition & FoodKeto Raised Tumor Counts in One Stretch of Mouse Gut and Cut Them in the Next, While the Ketones Sat It Out
In cancer-prone mice, a ketogenic diet meant more small-intestine tumors and fewer colon tumors, and the ketones long credited for keto's anticancer promise turned out to be bystanders.
Brain & AgingAlzheimer's Drugmakers Bet on Raising This Brain Sugar. Glucosamine May Be Overfeeding It.
In UF Health records, people with mild cognitive impairment who took the joint supplement were 25 percent more likely to slip into dementia. Glucosamine feeds the same brain chemistry a failed Alzheimer's drug was built to raise.
Brain & AgingScientists Quieted Aging Inflammation in Mice by Starving Zombie Cells, Not Killing Them
For years the anti-aging plan was to hunt down and kill the senescent cells driving inflammation. A Mayo and Sanford Burnham team quieted that inflammation in mice instead, by blocking the carrier that feeds their mitochondria the acetyl-CoA used to pry open inflammatory genes.
Metabolic & WeightBerkeley Dusted Off a Shelved 1970s Fat Compound That Burns Energy Instead of Appetite, and in Mice It Spared the Muscle
GLP-1 drugs quiet your appetite, and along with the fat they can pull out a real chunk of muscle. A shelved acetyl-CoA carboxylase inhibitor from the 1970s went after the other lever, energy burned, and in obese mice it left the lean mass alone.
Metabolic & WeightYour Fat Cells Remember Being Fat, and That Memory Outlasts the Weight Loss
Your body defends its heaviest weight for years after you lose it, which is why the rebound isn't weak willpower and why the injection only works while you keep paying for it.
Nutrition & FoodThey Doubled the Recommended Protein This Year. 350 Studies Say That's Backwards for Sedentary Adults.
Federal guidance now tells you to eat nearly twice the protein it used to. A University of Wisconsin review of more than 350 studies argues that for people who don't train hard, the extra may be speeding up the aging they're trying to outrun.
Autoimmune & InflammationA Chinese Bark Compound Reached the Black-Box Arthritis Drugs' Pathway From Upstream, in Rats
In rats, a compound from the bark of the Amur cork tree reached the same JAK-STAT pathway as Xeljanz and its black-box cousins, but by rebalancing the cell's fat metabolism instead of blocking the pathway directly.
Autoimmune & InflammationThe Allergy Cell Everyone Wanted Dead Turns Out to Run Your Gut Lining and Your Metabolism
Eosinophils were the villain of asthma and allergy, the cell whole-body drugs are built to erase. A decade of tissue biology says they also seal your gut, feed your antibodies, and tune your fat, and the trials never measured any of it.
Brain & AgingLongevity Clinics Sell Growth Hormone by the Vial. In Deep Sleep, Your Brain Makes It Free.
The muscle-building, fat-burning hormone that anti-aging clinics inject at a premium is the same one your hypothalamus releases every night you reach deep sleep. Berkeley mapped how, in mice, and the headline is already running ahead of the biology.
Metabolic & WeightSwitch Off One Protein Called Mitch, and Cells Start Eating Their Own Fat
Women with obesity carry more of it. Disable it in mice and they turn lean and muscular at once, the opposite of what the injectable weight-loss drugs do to your body.