gut-microbiome
17 stories tagged "gut-microbiome"
A Daily Fiber Powder Eased Knee Arthritis Pain, and People's Grip Got Stronger Too
Six weeks of inulin, a prebiotic sold by the tub, cut knee pain 1.11 points more than placebo and added 4.62 kilograms of grip strength in a Nottingham trial, while the gut hormone GLP-1 rose alongside.
Autoimmune & InflammationThe 10-Year Crohn's Prediction Model Has Never Left the Military Cohort That Built It
Antibodies against gut-bacteria flagella and Epstein-Barr virus shift years before Crohn's is diagnosed, but the models scoring an AUC of 0.90 were built and judged inside one mostly male group of U.S. service members, with no independent validation yet.
Brain & AgingA Gut Molecule Tied to Diabetes and Clogged Arteries Now Tracks With Alzheimer's Decline
In 1,196 cognitively healthy adults, the people with the most of one gut-made molecule in their blood declined fastest, and a genetic variant carried by about 43 percent was linked to higher levels.
Nutrition & FoodSame Calories on Paper, 116 Fewer Absorbed: What Your Gut Microbes Do With a Whole-Food Diet
On calorie-matched menus, 17 adults absorbed about 116 fewer calories a day eating whole foods than eating processed ones, with no measurable rise in hunger, and the century-old Atwater arithmetic undercounted the processed plate.
Nutrition & FoodForget You Ate Lunch and You'll Eat Another One: Your Memory Center Helps Run Your Appetite
Two amnesic patients ate a second full lunch minutes after the first. Rats with silenced meal-memory neurons came back to eat sooner. In healthy young adults, one week of waffles and fast food dulled both word recall and the normal drop in food craving after a full breakfast.
Metabolic & WeightMulberry Blunts Your Blood Sugar by Handing the Carbs to Your Gut Bacteria
Mulberry's post-meal glucose effect has been tested in people across 12 trials. The gut-microbiome makeover sold on the strength of it still exists only in mice and petri dishes.
Nutrition & FoodFive Coffee Companies Paid for the Study Behind the "Coffee Fixes Your Gut and Brain" Headlines
The headlines credit your morning cup with less stress, sharper memory, and a healthier gut. The study behind them was paid for by ISIC, the trade body funded by five coffee companies including illycaffè, Lavazza, and Tchibo.
Nutrition & FoodTwo Labs on Two Continents Watched a Pomegranate Compound Relax Stiff Mouse Hearts
Heart failure with preserved ejection fraction has few disease-modifying options. A gut metabolite from pomegranates and walnuts, already sold as a supplement, improved measures of heart function up to 80 percent in mice.
Metabolic & WeightCrash Diets Rewire Your Gut to Sabotage the Next One
In mice, transplanting the gut microbes of weight-cycled animals into healthy ones handed over the bingeing with them. Crash dieting reshapes the gut, and the diet industry keeps selling you the fix for damage its last plan made.
Metabolic & WeightAt the Dose the FDA Calls Safe, Two Sweeteners Reshaped the Guts of Mouse Grandpups That Only Drank Water
Chilean researchers fed mice sucralose and stevia at the doses the FDA calls safe. The metabolic marks showed up in grandpups that only drank water.
Nutrition & FoodYour Gut Bacteria Decide Whether Sorbitol Is Harmless or a Liver Problem
Sorbitol was sold for decades as the inert, guilt-free sugar swap. In zebrafish stripped of their gut bacteria, WashU researchers watched the intestine's own sorbitol reach the liver and feed the same fructose-metabolism pathway that packs on liver fat.
Metabolic & WeightYour Gut Remembers the Benzo You Quit Three Years Ago
Screen 2,509 people's guts against their prescription records and the fingerprint lingers: benzodiazepines, antidepressants and acid-reducers stay linked to a shifted microbiome years after the last pill, some rivaling antibiotics.
Autoimmune & InflammationHow Fiber Teaches a Self-Erasing Gut Wall to Remember for Two Weeks
Butyrate, the compound gut bacteria make from fiber, reprogrammed the intestinal lining of mice to keep raising IL-10 and blunting colitis for 2 weeks after the last dose, and the imprint held even in mice with no gut bacteria at all.
Nutrition & FoodCut the Fiber and Your Gut Bacteria Start Eating Your Own Gut Lining
Princeton isotope tracing found that when fiber runs short, gut bacteria strip protein off the mucus wall and churn out the same toxins that pile up in failing kidneys. Feed them whole plants and the chemistry flips.
Nutrition & FoodA Daily Scoop of Chicory Fiber Eased Knee Arthritis, and It Moved the Same Gut Hormone as Ozempic
Twenty grams of chicory fiber a day matched a physiotherapy app for knee arthritis pain, and only one person in the fiber group quit. The hormone it nudged is the one Ozempic is built to imitate.
Metabolic & WeightA Gut Microbe Was Feeding Ammonia to Sick Livers. A Michigan Peptide Cut Off the Supply in Monkeys.
The compound reversed severe fatty liver in monkeys by starving one ammonia-making gut bacterium. It also comes from a company its lead inventor founded, and no human has taken it for this.
Metabolic & WeightSleep apnea's heart damage may run through the gut, not the airway
Researchers at UCSD report that knocking out a single bile-acid receptor abolishes the arterial plaque sleep-apnea conditions would otherwise drive in mice. The mechanism fits the CPAP era's underwhelming trial record better than the airway story ever did.