Brain & Aging
107 stories · Page 2 of 5
Blood Pours Into the Mouse Cortex Seconds Before REM, Then the Neurons Run Low on Fuel Anyway
About 50 seconds before REM sleep starts, blood volume surges across a sleeping mouse's cortex. Then the neurons' usable energy drops sharply anyway, and no one can yet say what they are burning it on.
Brain & AgingI Track My REM Sleep Every Night. This Study Made Me Stop Trusting the Number.
The viral headline says more REM sleep guards you against 83 diseases. But a brain sliding toward Parkinson's shreds REM years before diagnosis, and the study's own two-year exclusion test quietly agrees.
Brain & AgingA Bendable Fiber Thinner Than Six Hairs Records, Doses, and Stimulates a Mouse Brain at Once
Silicon brain probes scar the tissue they're built to read. A soft optical fiber from Denmark records, doses, and stimulates neurons at once, in mice, with a pharma foundation and pending patents behind it.
Brain & AgingThe 'Supplement Reverses Aging' Headline Skips the Brain Surgery on the Mouse
The mouse study now going around as an anti-aging supplement win leaves out the part where the real reversal took a virus carrying a gene, injected into the hypothalamus.
Brain & AgingFreeze a Brain Cell Fast Enough and Its Bare Wires Turn Out to Be Strings of Pearls, Not Smooth Tubes
The bumps along the brain's thinnest fibers were written off as damage for a century. Johns Hopkins froze the tissue fast enough to catch them intact, and to watch them swell when the neuron fires hard.
Brain & AgingThe Cell Mistakes Its Own Broken DNA for a Virus, and the Panic Helps Wreck a Fast-Aging Fish
For decades the broken DNA got the blame. In fast-aging fish carrying a DNA-repair disorder, a major driver turned out to be the cell's own inflammatory overreaction, and silencing the sensor eased the ruin.
Brain & AgingSame Genes, Different Fold: A Fly Wing Regrows Only When Distant DNA Touches
Disturb the way the DNA folds after an injury, and the fruit fly still builds a normal wing but loses much of its power to repair one. The instructions to heal weren't only in the genes. They were in the shape.
Brain & AgingUSC Scanned 459 Aging Brains Across India. The Wiring Just Under the Cortex, Not the Gray Matter, Tracked Who Stayed Sharp.
In 459 older adults across India, healthier short-range wiring just beneath the cortex was tied to a weaker link between gray matter loss and cognition, and the tie was strongest in people with the least schooling.
Brain & AgingScientists Quieted Aging Inflammation in Mice by Starving Zombie Cells, Not Killing Them
For years the anti-aging plan was to hunt down and kill the senescent cells driving inflammation. A Mayo and Sanford Burnham team quieted that inflammation in mice instead, by blocking the carrier that feeds their mitochondria the acetyl-CoA used to pry open inflammatory genes.
Brain & AgingFour Times the Odds of Losing Bowel Control: An ADHD Gut Signal Tangled Up With the Medication
Stimulants list constipation, nausea, and stomach pain among their common side effects. Most of the 23 studies pooling 1.9 million people never separated the medicated from the unmedicated, so the gut signal and the drug effect sit tangled together.
Brain & AgingA Kinesiologist Argues Aging Has a Third Clock, and It Fades First
Georgia Southern's Li Li argues aging has a third clock, movement span, that starts narrowing before any disease shows up. A compelling reframe with one catch: it's an opinion paper carrying zero new data.
Brain & AgingThe Sea Squirt That Reverses Aging Is a Mouse Study From 2022. The Capsules Are Already on Amazon.
The mice got 300 milligrams per kilogram by feeding tube, five days a week, for two months. The human trials used about a milligram a day, most were funded by the companies selling the capsules, and the largest could not beat placebo.
Brain & AgingStatins and Dementia: A Benefit the Registries Keep Finding and the Trials Never Do
A Danish registry of 132,000 diabetics reports early statin use lowers dementia risk by 15 percent. The randomized trials that could confirm it, covering tens of thousands of patients, found nothing.
Brain & AgingA Salsa Class, a Grocery List, and 38 Check-Ins Beat Health Advice on Memory by 55%
Across 11 Latin American countries, a coached program of exercise, an adapted MIND diet, and cognitive training improved older adults' thinking 55 percent more than periodic health advice, with no infusion chair and no $26,500-a-year drug.
Brain & AgingDirty Air Is Linked to 16 Percent More Inflammation in Your Blood. Does That Damage Reach Your Brain?
Each step up in long-term fine-particle exposure is tied to nearly 16 percent higher inflammation in older adults' blood, and a CHARLS analysis asks whether that same signal is what wears down the aging brain.
Brain & AgingAutistic Teenagers Are Bullied Three Times as Often, and We Have Barely Studied How to Protect Them
Autistic teenagers are bullied roughly three times as often as their peers, and the sexual-victimization risk that shadows them into adulthood is just as real, yet the research meant to protect them is small, scattered, and looking the other way.
Brain & AgingThe Amino Acid Sold for Focus Tracked Fewer Years for Men, Not Women
In more than 270,000 people, men with higher blood tyrosine died sooner, by nearly a year on the genetic estimate. Women showed no clear lifespan signal. The amino acid is sold in capsules for focus.
Brain & AgingThey Didn't Rewrite the Memory. A Flinch of Surprise Predicted Who Got Better.
Polish researchers had 180 young adults imagine a defender stepping into a painful childhood memory. The rewrite itself helped only modestly. What predicted who improved was an involuntary jolt of surprise, measured in the skin, when the expected blow never came.
Brain & AgingThe Calm-Down Breath That Made People Bet Bigger
A 2-second inhale and an 8-second exhale slowed 41 people's hearts and, across the same sessions, made them more willing to take the risky bet. The pull came from the reward side, not from any loss of caution.
Brain & AgingA Stanford Lab Deleted One Immune Receptor and Its Old Mice Barely Aged
Stanford says it found one big reason we age. The proof is a genetically engineered mouse, no such drug exists for people, and the senior author already holds patents on inhibiting the receptor she wants blocked.
Brain & AgingThe ADHD Creativity Bump Is Modest, and It Fades Right Where the Symptoms Turn Clinical
The headlines sell the wandering ADHD mind as a hidden creative gift. The data underneath shows the edge is modest and flattens right as symptoms cross into the clinical range.
Brain & AgingChronic Money Trouble Showed Up on the Brain Scans, Decades Later
In a British cohort followed since birth, people who spent years in the bottom fifth of income had weaker verbal memory by their fifties and larger brain ventricles, a marker of brain aging, by their seventies, even after childhood and education were accounted for.
Brain & AgingIn Mice, Early-Life Stress Writes a Molecular Mark Onto the Brain's Reward Neurons. Turn One Enzyme Down, and It Never Sets
Early-life stress raises an enzyme called SETD7 in the brain's dopamine neurons, loosening the DNA around stress genes so they fire too easily into adulthood. When researchers blocked it in mice, the stressed animals did not develop the same anxiety-like stress sensitivity, and stayed as social and
Brain & AgingIn Depressed Brains, the New-Neuron Supply Had Stalled Where Fresh Pain Gets Sorted From Old
Columbia researchers mapped nearly 500,000 cells from postmortem brains and found the depressed ones showed a stalled supply of new hippocampal neurons, the cells thought to keep a fresh setback from merging with every old one.